Mizanur Rahman

Cerebrovascular diseases have recently emerged as a major health problem affecting the elderly population. Volume of the blood is one factor which can determine the prognosis of the patient with intracerebral hemorrhage. A prospective observational study was done at Neurology ward of Chittagong Medical College Hospital (CMCH). The aim of this study was to determine the 30-day mortality of intracerebral hemorrhage in a hospital population and to determine the most important predictor of 30-day outcome. Seventy cases of spontaneous intracerebral hemorrhage were analyzed and followed up for 30 days in hospital and house where necessary. Statistical analyses were performed to see the outcome in relation with blood volume by SPSS-18. In this study, 50(71.42%) patients had hypertension. Diabetes mellitus was found among 6(8.57%). aphasia was found 40(57.1%) patients, dysarthria was in 11(15.7%), motor deficit in 65(92.9%) patients, 48(68.6%) patients had cranial nerve involvement and 32(45.7%) patients had abnormal fundoscopic findings. Regarding analysis of volume of hemorrhage, <5 ml was found in 9(12.9%) patients, 5-15 ml was found in 32(45.7%) patients, >15-30 ml was found in 15(21.4%) patients, >30-60 ml was found in 10(14.3%) patients and >60 ml was in 4(5.7%) of patients. Among all patients, no of death was 9(12.8%) within 30 day and rest 61(87.2%) were alive. After analysis, it was found that fatal outcome is more with increased volume of hemorrhage (p<0.05). It was 100% with >60ml of hemorrhage. Volume of intracerebral hemorrhage is a powerful and easy-to-use predictor of 30-day mortality in patients with spontaneous intracerebral hemorrhage.

Diabetes mellitus (DM) is a metabolic disorder of multiple aetiology characterized by chronic hyperglycemia with disturbances of carbohydrate,fat and protein metabolism resulting from defects in insulin secretion, insulin action,or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. A case-control study was carried out in Chittagong Medical College, Chittagong, Bangladesh during the period of January 2012 to December 2012. The samples were collected from the department of Medicine, Chittagong Medical College Hospital. The age limits of the patients were from 30-70 years. The data were collected by a structured questionnaire including age, sex, blood pressure, total cholesterol. Total numbers of patients were 90 of which 50 were considered as cases (All type-II diabetic patients having (i) age 30-70 years (ii) Fasting blood sugar ≥ 7 mmol /L. (iii) Random blood sugar ≥11.1 mmol/L. (iv) 2 hrs. after oral glucose load is ≥ 11.1mmol/L and 40 controls (non-diabetic, age 30-70 years, absence of renal, liver and cardiovascular diseases). The study was designed to observe the postprandial triglyceride level in type-II diabetic patients. The mean fasting triglyceride level of cases was 210.70 (±19.5) and the 2hrs, 4hrs and 6hrs after test meals were 238.9 (±22.75), 260.5 (±15.36), and 260.32 (±5.94) respectively. At the same time the mean fasting triglyceride of the control was 173.75 (±19.86) and the corresponding mean of the control were 189.75 (±15.23), 174.38 (±16.49) and 173.88 (±15.79) mg/dl respectively. The fasting and postprandial (2hrs, 4hrs and 6hrs) triglyceride levels were significantly higher than that of corresponding control. There are also significant differences of triglyceride level in fasting and 2hrs, 4hrs and 6hrs after test meal among the cases which indicated that the triglyceride levels remained eleva