Assessment of Liver Enzymes Levels among Sudanese Hyperthyroidism Patients

Thyroid hormones regulate the metabolisms of all cells including hepatocytes, and hence, modulate hepatic function .Thyroid disorders often accompany abnormal serum enzyme levels and disturbances in liver functions, this study aim to assess relationship between serum enzymes and liver functions in thyroid disorders. 40 cases of hyperthyroidism and 40 controls were induced in this study by convenience sampling. Their liver enzyme profile for aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were determined and analyzed for correlation. Three variables were measured for all cases and controls, plasma level activity of liver specific enzymes ALT, AST and ALP. The mean values between cases and controls showed a significant increase in ALP and ALT and no significant difference was shown in AST. Also a correlation was found between age, gender and ALP among cases while no correlation was found in AST and ALT.