British Journal of Medical and Health Research BJMHR 2394-2967 BJMHR0303005 Assessment of Liver Enzymes Levels among Sudanese Hyperthyroidism Patients Ahmed Suhair A Ibrahim Mona Osman Idris Omer Fadl Faculty Of Medical Laboratory Sciences, Department Of Clinical Chemistry, University Of ALneelain, Khartoum, Sudan Department of Clinical Chemistry, Faculty of Medical Laboratory Science, University AL Neelain University,Sudan Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, AL Neelain University,Sudan 03 01 2016 3 3

Thyroid hormones regulate the metabolisms of all cells including hepatocytes, and hence, modulate hepatic function .Thyroid disorders often accompany abnormal serum enzyme levels and disturbances in liver functions, this study aim to assess relationship between serum enzymes and liver functions in thyroid disorders. 40 cases of hyperthyroidism and 40 controls were induced in this study by convenience sampling. Their liver enzyme profile for aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were determined and analyzed for correlation. Three variables were measured for all cases and controls, plasma level activity of liver specific enzymes ALT, AST and ALP. The mean values between cases and controls showed a significant increase in ALP and ALT and no significant difference was shown in AST. Also a correlation was found between age, gender and ALP among cases while no correlation was found in AST and ALT.

 Hyperthyroidism liver enzymes AST ALT ALP Sudan.