Jahangir Khan

Cerebrovascular diseases have recently emerged as a major health problem affecting the elderly population. Volume of the blood is one factor which can determine the prognosis of the patient with intracerebral hemorrhage. A prospective observational study was done at Neurology ward of Chittagong Medical College Hospital (CMCH). The aim of this study was to determine the 30-day mortality of intracerebral hemorrhage in a hospital population and to determine the most important predictor of 30-day outcome. Seventy cases of spontaneous intracerebral hemorrhage were analyzed and followed up for 30 days in hospital and house where necessary. Statistical analyses were performed to see the outcome in relation with blood volume by SPSS-18. In this study, 50(71.42%) patients had hypertension. Diabetes mellitus was found among 6(8.57%). aphasia was found 40(57.1%) patients, dysarthria was in 11(15.7%), motor deficit in 65(92.9%) patients, 48(68.6%) patients had cranial nerve involvement and 32(45.7%) patients had abnormal fundoscopic findings. Regarding analysis of volume of hemorrhage, <5 ml was found in 9(12.9%) patients, 5-15 ml was found in 32(45.7%) patients, >15-30 ml was found in 15(21.4%) patients, >30-60 ml was found in 10(14.3%) patients and >60 ml was in 4(5.7%) of patients. Among all patients, no of death was 9(12.8%) within 30 day and rest 61(87.2%) were alive. After analysis, it was found that fatal outcome is more with increased volume of hemorrhage (p<0.05). It was 100% with >60ml of hemorrhage. Volume of intracerebral hemorrhage is a powerful and easy-to-use predictor of 30-day mortality in patients with spontaneous intracerebral hemorrhage.

Childhood Obesity is a major cause of mortality and morbidity around the world. Its prevalence is increasing dramatically regardless of age and geographical variation becomes a serious public health problem. A cross sectional comparative study was conducted in the Department of Biochemistry, Chittagong Medical College, Bangladesh during the period from July 2013 to June 2014. The aim of the study was to evaluate the relationship between serum lipid profile with childhood overweight and obesity. Total 100 subjects were included in this study. Among them 50 were Case (Group A) whose BMI was ≥85th percentile and 50 were Control (Group B) whose BMI (Body Mass Index) was >5th percentile to 84th percentile. Serum Total cholesterol, LDL-C (Low Density Lipoprotein Cholesterol), HDL-C(High Density Lipoprotein Cholesterol) and TG(Triglyceride) were measured in all samples in fasting state. The test statistics used to analyze the data were descriptive statistics, Chi-square (X2) test, Student’s t-Test and Correlation co-efficient. The average BMI of cases were 25.91±3.67 kg/m2 and controls were 19.12±2.10kg/m2. The mean weight of cases were 58.30±12.70 kg and controls were 46.08±8.19kg.The mean serum LDL in cases was 104.28±19.70 mg/dl and control was 77.22±19.14 mg/dl.. The mean serum TG in cases was 120.80±33.20mg/dl and control was 83.78±20.33mg/dl. In cases the mean serum HDL-C was 43.40±4.01 mg/dl and control was 45.56±4.48 mg/dl respectively. Pearson’s correlation coefficient(r) showed that there was a positive correlation between BMI and total cholesterol(r=+0.535, p=<0.005) BMI and LDL-C(r=+0.520, p=<0.005), BMI and TG (r=+0.550, p=<0.05) and negative correlation between BMI and HDL-C(r= -0.27, p=<0.005)