Childhood obesity

Childhood Obesity is a major cause of mortality and morbidity around the world. Its prevalence is increasing dramatically regardless of age and geographical variation becomes a serious public health problem. A cross sectional comparative study was conducted in the Department of Biochemistry, Chittagong Medical College, Bangladesh during the period from July 2013 to June 2014. The aim of the study was to evaluate the relationship between serum lipid profile with childhood overweight and obesity. Total 100 subjects were included in this study. Among them 50 were Case (Group A) whose BMI was ≥85th percentile and 50 were Control (Group B) whose BMI (Body Mass Index) was >5th percentile to 84th percentile. Serum Total cholesterol, LDL-C (Low Density Lipoprotein Cholesterol), HDL-C(High Density Lipoprotein Cholesterol) and TG(Triglyceride) were measured in all samples in fasting state. The test statistics used to analyze the data were descriptive statistics, Chi-square (X2) test, Student’s t-Test and Correlation co-efficient. The average BMI of cases were 25.91±3.67 kg/m2 and controls were 19.12±2.10kg/m2. The mean weight of cases were 58.30±12.70 kg and controls were 46.08±8.19kg.The mean serum LDL in cases was 104.28±19.70 mg/dl and control was 77.22±19.14 mg/dl.. The mean serum TG in cases was 120.80±33.20mg/dl and control was 83.78±20.33mg/dl. In cases the mean serum HDL-C was 43.40±4.01 mg/dl and control was 45.56±4.48 mg/dl respectively. Pearson’s correlation coefficient(r) showed that there was a positive correlation between BMI and total cholesterol(r=+0.535, p=<0.005) BMI and LDL-C(r=+0.520, p=<0.005), BMI and TG (r=+0.550, p=<0.05) and negative correlation between BMI and HDL-C(r= -0.27, p=<0.005)