“EFFECT OF LEAVES AND FRUITS OF MORINGA OLEIFERA LAM ON GASTRIC AND DUODENAL ULCERS IN RATS”

Abstract: Plant Moringa oliefera ( family –Moringaceae) is a exceptionally nutritious vegetable tree with a variety of potential uses. In the present study, Effect of leaves and fruits of Moringa oleifera plant were studied on gastric and duodenal ulcers using methanol and acetone extraction. The antiulcer activity was performed by using two models Ethanol induced gastric ulcers and Cysteamine induced ulcers. The fruit extracts of the plant did not show any significant effect on the healing of gastric ulcers, Whereas the methanol and acetone leaf extracts increased the healing effect . The healing of ulcers in ethanol–induced gastric ulcers may be due to decreased acid secretion, increased or decreased GI motility incase of methanol and acetone extracts, and the ulcer healing effect is mainly due to reduction in gastric motility.