Type-2 Diabetes Mellitus

Currently available data is limited in estimating the demography of Type 2 Diabetes Mellitus (T2DM) patients and hence this study helps in understanding the disease profile, associated complications, comorbidities, treatment paradigms and socio-economic impact in T2DM patients across India. A multicenter, observational, non-interventional, 6 month follow-up registry was conducted in 26 states across India involving 2944 T2DM patients between 18-75 years of age. Detailed medical history, profile of patients, diet patterns and lifestyle methods were captured. The laboratory parameters like FBG, PPBG and HbA1c were captured at enrolment, 3rd and 6th months. Out of total 2944 patients, data of 2849 (96.77%) patients were considered for analysis. The mean age of patients with diabetes was 52.9 years with mean diabetes duration of 5.8 years. About 1/4th of diabetics were hypertensive (24.05%) and majority was from the upper middle socio-economic strata (42.6%). About 15.8% patients were never advised lifestyle modifications and non-pharmacological interventions during the physician interaction. Metformin was the most commonly used oral hypoglycemic drug (58.53%) followed by glimepiride (35.87%); whereas a combination of metformin and glimepiride was used in 16.98% patients. Good glycemic control (HbA1c<7%) is observed only in 20.8% and 23.4% patients at 3rd and 6th months. Non-compliance to diabetic diet is found in 8% individuals. The most common cause of non-compliance is lack of motivation (5.54%), lack of information (2.28%), busy job schedules (1.94%) and financial reasons (1.56%). The one diabetes registry helps in understanding the T2DM patient flow, comorbid conditions and compliance to therapy from Indian perspective.