Intervention

Mental health interventions encompass a broad-spectrum including promotion, prevention, early intervention, treatment, recovery, and maintenance. However, the specific roles of various social settings and tools—such as schools, social services, and digital platforms—remain inadequately understood or integrated. This systematic review aimed to establish evidence-based insights into the roles of these settings and tools in the early detection and intervention of adolescent mental health disorders in the United Kingdom (UK). A comprehensive search of six electronic databases was conducted between the 8th and 19th of April 2025, supported by policy documents and supplemented by reference list screening of included and review articles. The search strategy was guided by the PIOS framework. Out of 9,325 citations screened, 12 studies met the inclusion criteria. These studies, published between 2016 and 2023, focused on adolescents aged 8 to 25 years and addressed various disorders, including social anxiety disorder. There is need for integration and multidisciplinary collaboration to increase the extent and effectiveness of mental health interventions. Albeit digital tools or online delivery approach offers the opportunity to overcome many of the limitations associated with school-based tools. However, consistent data collection across the social service, health and education settings, an all-encompassing information can be generated to support the understanding of individuals’ exposure to risk factors for mental health problems. Keywords: Mental Health, Early Detection, Intervention, Schools, Social Services, Digital Technologies

• Objectives: The aim of the study was to improve the standard of living in patients with Asthma and Chronic obstructive pulmonary disease by intervention and patient counseling. • Methods: This Prospective interventional study was carried out in general medicine department RIMS for 6 months. Both old and new asthma and COPD Patients were included. Statistical Analysis was performed to find the statistical significance difference among all the study groups. • Results: In our study we had recruited 100 patients of which we categorized based on gender, age, occupation and risk factors, the majority of patients in the gender were females in asthma and males in COPD, age group between 51-60(n=33, 55%), in occupation coolie group(n=43, 71.66%), and in risk factor were smoker (n=52, 54.16%). • Conclusion: This study concluded that the clinical pharmacist can play a positive role in the control of patients, to prevent recurrences, reduce progression of disease and ultimately minimize hospitalization.

Breast cancer is the most common cancer among women. The number of breast cancer survivors has increased due to screening and improved treatment methods, which makes it important to increase knowledge on their health and well-being. Physical activity has been reported to improve quality of life, decrease fatigue and reduce all-cause and breast cancer-specific mortality in breast cancer survivors. In physically active subjects, the risk reduction averaged 25–30%. Breast cancer is one of the most commonly diagnosed types of cancer in women. Its pathogenesis involves genetic, hormonal, and environmental factors6. A large body of evidence indicates that physical activity has positive effects on every aspect of breast cancer evolution, including prevention, medical treatment, and aftercare clinical settings. Thus, different types of exercise can influence the prevention and progression of the disease through several common mechanisms, such as reduction of insulin resistance and improvement of immunity and cardiovascular function. Furthermore, acute and chronic symptoms of breast cancer, such as cachexia, muscle mass loss, fatigue, cardiotoxicity, weight gain, hormone alterations, bone loss, and psychological adverse effects, may all be favorably influenced by regular exercise.7 The potential role of exercise in reducing the intensity of the adverse effects that result from breast cancer and anticancer treatment is also discussed1. According to published data, 30–60 min of exercise per day at a moderate intensity is regarded as the optimal duration. Furthermore, physical activity plays an important role in the therapy of breast cancer, not only after finishing but already during treatment. The beneficial effects of physical activity may manifest themselves in circulating levels of insulin, insulin-growth factors (IGFs) I and II and their binding proteins (IGFBPs), or inflammatory biomarkers. The aim of this report was to review available randomized controlled trials (RCTs) on the effects of physical activity on biomarkers in breast cancer survivors. Five RCTs reported statistically significant effects of physical activity on insulin, IGF-I, IGF-II and IGFBP-3 in breast cancer survivors, but the results were not consistent. None of four RCTs found any evidence for a role of investigated interleukins. One trial reported some evidence that exercise may decrease C-reactive protein levels. In conclusion, available RCTs have produced some evidence that physical activity may result in beneficial changes in levels of insulin, IGFs, IGFBPs, and inflammatory biomarkers in breast cancer survivors. However, further larger RCTs on physical activity and biomarkers in breast cancer survivors are warranted.