Antiinflammatory

Methodology- A total of 300 subjects aged 25-75 years were selected from reputed hospitals based on inclusion criteria. Data on demographics, medical history, dietary intake through FFQ and 24-hour dietary recall, anthropometric measurements, handgrip strength, inflammatory & nutritional biomarkers were analysed. Results- Nutrient intake analysis showed 270 subjects had inadequate daily intake of protein, essential fatty acids, calcium, phosphorus, and zinc. BMI was normal (21.1±1.21 kg/m²) among subjects n=93 subjects, n=160 were overweight/obese (25.54±1.98 kg/m²), n=24 were undernourished (16.93±1.43 kg/m²). Handgrip strength was weak in 210 subjects, 85 were normal, and only 5 were strong. Clinical signs & symptoms, including joint pain, swelling and stiffness, were mild in males and moderate in females. Nutritional biomarkers showed normal calcium (8.63±0.66mg/dl) and hemoglobin (14.01±0.27g/dl) levels in males but low calcium (7.99±0.12mg/dl) and hemoglobin (11.82±0.08g/dl) levels in females. Inflammatory markers, ESR (76.74±27.26mm/hr) and CRP (36.67±20.24mg/dl), were higher in females compared to males ESR (43±17.51mm/hr) and CRP (25.68±5.20mg/dl). Conclusion- The evidence suggests the need for nutrient-dense diet, focusing more on protective-nutrients such as protein, calcium, iron, and essential fatty acids with antioxidant and anti-inflammatory potential. A holistic approach combining medical and nutrition therapy is recommended for better RA management and improved quality of life.