Skip to main content
9409046853
e-ISSN: 2394-2967
British Journal of Medical and Health Research

British Journal of Medical and Health Research

LoginTrack Your Paper
Published

Non-Hodgkin Lymphoma Mimicking an Antibioma Following Dental Extraction

,

Published in September 2026 Issue 09 (Vol. 13, Issue 9, 2026)

Non-Hodgkin Lymphoma Mimicking an Antibioma Following Dental Extraction - Issue cover

Keywords

Non-Hodgkin lymphoma; diffuse large B-cell lymphoma; oral lymphoma; buccal space; dental extraction; paresthesia; antibiomalymphoid malignanciesantibiomaodontogenic infection

Abstract

Non-Hodgkin lymphoma (NHL) comprises a heterogeneous group of lymphoid malignancies with clinical behaviour ranging from indolent to highly aggressive. These neoplasms arise from lymphoid cells at different stages of differentiation, and their biological characteristics reflect their cellular origin. Intraoral NHL is uncommon and may involve either the jaw bones or the soft tissues of the oral cavity. We report the case of a 54-year-old man who presented with persistent buccal space swelling following extraction of the mandibular right second molar (tooth 47) for presumed odontogenic infection. Despite antibiotic therapy, the swelling progressively increased in size and was associated with the development of lower-lip paresthesia. An initial clinical diagnosis of antibioma was made; however, the persistence and progression of the lesion prompted further investigation. Histopathological examination and immunohistochemical analysis established a diagnosis of diffuse large B-cell lymphoma (DLBCL). This case highlights the importance of considering malignant disease in the differential diagnosis of persistent or progressive orofacial swellings, particularly when presumed odontogenic lesions fail to respond to appropriate treatment or are accompanied by neurosensory disturbances.

References

  1. [1]Bowzyk Al-Naeeb A, Ajithkumar T, Behan S, Hodson DJ. Non-Hodgkin lymphoma. BMJ. 2018;362:k3204. DOI: https://doi.org/10.1136/bmj.k3204.
  2. [2]Meena JP, Gupta AK, Parihar M, Seth R. Clinical profile and outcomes of non-Hodgkin’s lymphoma in children: A report from a tertiary care hospital from India. Indian J Med Paediatr Oncol. 2019;40:41–47. DOI: 10.4103/ijmpo.ijmpo_70_18.
  3. [3]Extranodal Non-Hodgkin’s Lymphoma of the Oral Cavity: A Case Report.
  4. [4]Bachaud JM, Coppin D, Douchez J, Boutault F, Paty E, Saboye J, et al. Primary malignant lymphoma of the mandible: A study of 3 cases and review of the literature. Rev Stomatol Chir Maxillofac. 1992;93:372–376. [PubMed] [Google Scholar]PubMedGoogle Scholar
  5. [5]Djavanmardi L, Oprean N, Alantar A, Bousetta K, Princ G. Malignant non-Hodgkin’s lymphoma of the jaws: A review of 16 cases. J Craniomaxillofac Surg. 2008;36:410–414. doi: 10.1016/j.jcms.2008.03.004. [DOI] [PubMed] [Google Scholar]DOIPubMedGoogle Scholar
  6. [6]Parrington SJ, Punnia-Moorthy A. Primary non-Hodgkin’s lymphoma of the mandible presenting following tooth extraction. Br Dent J. 1997;187:468–470. doi: 10.1038/sj.bdj.4800308. [DOI] [PubMed] [Google Scholar]DOIPubMedGoogle Scholar
  7. [7]Primary non-Hodgkin’s lymphoma of mandible: A rare entity. Dr Channabasappa Kori, Dr Jeevan Vishnoi, Dr D Prashant Kumar, Dr Shashi Singh Thakur, Dr Sameer. Sch J Med Case Rep. 2015;3(7):635–638. Non-Hodgkins Large B cell lymphoma, negative for CD3 immunostain. (CD3 stain. X400) Figure 6 Figure 7

Authors (2)

Jaliya moitheen.R

MOH Kuwait

View all publications →

Dr.Mijil Anand Justin

Department of histopathology, ...

View all publications →

Download Article

PDF

Best for printing and citation

File size: 0.9 MB
Format: PDF
ViewDownload

Summarise this paper with AI:

GoogleGooglePerplexityPerplexityGrokGrokChatGPTChatGPTClaudeClaude

Article Information

Published in:

September 2026 Issue 09 (Vol. 13, Issue 9, 2026)

BJMHR9130004

BJMHR-13-000064

39-47

2026-09-16

JATS XML

Article Impact

Views:4,526
Downloads:1,302

How to Cite

moitheen.R, J., & Anand Justin, D. (2026). Non-Hodgkin Lymphoma Mimicking an Antibioma Following Dental Extraction. British Journal of Medical and Health Research, 13(9), 39-47. https://bjmhr.com/articles/BJMHR9130004

Article Actions

Whatsapp