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British Journal of Medical and Health Research

British Journal of Medical and Health Research

📢 Latest Update: 🔔 Call for Papers 2026 | BJMHR Now Accepting Manuscripts for September 2026 Issue | Peer-Reviewed | Open Access | Fast Review in 5–7 Days | Submit Now

📢 Latest Update: 🔔 Call for Papers 2026 | BJMHR Now Accepting Manuscripts for September 2026 Issue | Peer-Reviewed | Open Access | Fast Review in 5–7 Days | Submit Now

Volume 13, Issue 9 - 2026 (September 2026 Issue 09)

Volume 13 Issue 9 Cover

Issue Details:

Volume 13 Issue 9
Published:Sep 1, 2026

Editorial: September 2026 Issue 09

Welcome to the 2026 issue of British Journal of Medical and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr J S Patel
Editor in Chief
British Journal of Medical and Health Research

Articles in This Issue

Showing 6 of 6 articles
Systematic reviewsID: BJMHR9130001Pages 1-17Open AccessOpen Access

Recent Emerging Molecular Target for Diabetes: A Comprehensive Review

Dr.Jagpal Singh, Dr. Ankita Singh, Ashok Kumar, Ritakshi, Dr. Girendra kumar Gautam

Type 2 diabetes, a chronic metabolic disorder that includes consistent high blood sugar levels, presents an extensive health problem around the globe. Traditional therapeutic approaches, including insulin therapy and oral hypoglycaemic agents, have been the cornerstone of diabetes management for decades. However, these conventional treatments often fall short in addressing the multifaceted nature of the disease and its complications. Recent advancements in molecular biology have unveiled novel targets that offer promising avenues for more effective and personalized diabetes management. This paper provides emerging molecular targets, MTOR, comparing these approaches, we aim to highlight the potential and integrating these targets to enhance treatment outcomes, reduce complications, and improve the quality of life for individuals with diabetes. Previous research studies confirm the effects of various diets on glycaemic management, growth rates, and quality of life, focusing on type 1 diabetes mellitus and celiac disease. There is limited research on the impact of a gluten-free, carbohydrate-counting diet on glycaemic management, growth, and quality of life in individuals with both celiac disease and type 1 diabetes mellitus. Mammalian Target of Rapamycin conventionally well-known target for the cancerous study, although MTOR have have the continuous impact the diabetic study moreover extensively focuses for the utilization and management of the glucose, lipid profile, and weight in patients, but few studies substantiate these benefits the included genetic patterns.

Diabetes mellitusDPP-4 inhibitorsSGLT2 inhibitorsAMPKand TGF-β signalling.
68,939 views
20,749 downloads

Contributors:

 Dr.Jagpal Singh
,
 Dr. Ankita Singh
,
 Ashok Kumar
,
 Ritakshi
,
 Dr. Girendra kumar Gautam
Case reportsID: BJMHR9130002Pages 18-29Open AccessOpen Access

Salvaging Hopeless Teeth by Hemisection: Two Case Reports with 1-Year Follow-up

Nancy Budakoti, Afaf Zia, Aisha Samreen, Adeela Majid

Background: Endo-periodontal lesions (EPL) present considerable diagnostic and therapeutic challenges. Hemisection, when appropriately indicated, serves as a conservative alternative to extraction in multirooted teeth. Case Presentation: This report presents two separate cases in which mandibular molars exhibit EPL with localized root damage. Following comprehensive endodontic and periodontal evaluation, the non-salvageable distal root was resected, and the remaining mesial root was preserved. Treatment included nonsurgical root canal therapy, full-thickness flap surgery, debridement, hemisection and socket preservation using demineralized freeze-dried bone allograft (DFDBA), platelet-rich fibrin (PRF), and a collagen membrane. Both cases were rehabilitated with a fixed partial denture. 12-month postoperative follow-up of both cases demonstrated successful clinical and radiographic outcomes, including stable periodontal parameters and restored function. Conclusion: Hemisection remains a viable option for preserving function and natural dentition in selected cases of EPL with localized root damage.

Endo-periodontal lesionFurcation involvementHemisectionPrognosisPulp
69,084 views
20,816 downloads

Contributors:

 Nancy Budakoti
,
 Afaf Zia
,
 Aisha Samreen
,
 Adeela Majid
Clinical trialsID: BJMHR9130003Pages 30-38Open AccessOpen Access

Platinum Plus Immunotherapy Versus Platinum Alone in Triple-Negative Breast Cancer: A Systematic Review

Dr. Animesh Kumar Mishra, Dr. Parmita Roy, Dr. Silky Kumari, Shubhartha Kayal

Triple-negative breast cancer (TNBC) represents approximately 15–20% of all breast cancers and is characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. TNBC is associated with aggressive clinical behavior , higher rates of visceral metastasis, earlier recurrence, and poorer overall prognosis compared to other breast cancer subtypes. Cytotoxic chemotherapy has historically remained the mainstay of systemic treatment. Among available agents, platinum compounds such as carboplatin and cisplatin have demonstrated particular activity because TNBC frequently exhibits defects in homologous recombination DNA repair pathways, including BRCA1/2 dysfunction. In recent years, immune checkpoint inhibitors against programmed death-1 (PD-1) or programmed death-ligand 1 (PD-L1) have emerged as promising therapeutic strategies. Combining immunotherapy with platinum-based chemotherapy may enhance antitumor immunity and improve outcomes. Objective To conduct a systematic review of existing evidence that contrasts the use of platinum combined with immunotherapy against platinum alone in individuals with early-stage and metastatic TNBC, with an emphasis on evaluating efficacy, survival rates, pathological complete response, and safety. Results Significant trials such as KEYNOTE-355, KEYNOTE-522, IMpassion130, IMpassion031, GeparNuevo, NeoTRIPaPDL1, along with various pooled analyses, have shown enhanced pathological complete response (pCR), progression-free survival (PFS), event-free survival (EFS), and overall survival (OS) in specific TNBC groups receiving platinum combined with immunotherapy, as opposed to chemotherapy alone. The advantages were particularly evident in PD-L1-positive metastatic TNBC and early-stage II–III TNBC. Nonetheless, the incidence of immune-related adverse events was higher in the arms receiving combination therapy. Conclusion Conclusion present data indicate that combining platinum with immunotherapy offers a more effective treatment approach than using platinum by itself for carefully chosen patients with TNBC. It remains crucial to select patients based on biomarkers and to manage toxicity effectively.

Platinum Plus ImmunotherapyTriple-negative breast cancerestrogen receptor
69,555 views
20,840 downloads

Contributors:

 Dr. Animesh Kumar Mishra
,
 Dr. Parmita Roy
,
 Dr. Silky Kumari
,
 Shubhartha Kayal
Case reportsID: BJMHR9130004Pages 39-47Open AccessOpen Access

Non-Hodgkin Lymphoma Mimicking an Antibioma Following Dental Extraction

Jaliya moitheen.R, Dr.Mijil Anand Justin

Non-Hodgkin lymphoma (NHL) comprises a heterogeneous group of lymphoid malignancies with clinical behaviour ranging from indolent to highly aggressive. These neoplasms arise from lymphoid cells at different stages of differentiation, and their biological characteristics reflect their cellular origin. Intraoral NHL is uncommon and may involve either the jaw bones or the soft tissues of the oral cavity. We report the case of a 54-year-old man who presented with persistent buccal space swelling following extraction of the mandibular right second molar (tooth 47) for presumed odontogenic infection. Despite antibiotic therapy, the swelling progressively increased in size and was associated with the development of lower-lip paresthesia. An initial clinical diagnosis of antibioma was made; however, the persistence and progression of the lesion prompted further investigation. Histopathological examination and immunohistochemical analysis established a diagnosis of diffuse large B-cell lymphoma (DLBCL). This case highlights the importance of considering malignant disease in the differential diagnosis of persistent or progressive orofacial swellings, particularly when presumed odontogenic lesions fail to respond to appropriate treatment or are accompanied by neurosensory disturbances.

Non-Hodgkin lymphoma; diffuse large B-cell lymphoma; oral lymphoma; buccal space; dental extraction; paresthesia; antibiomalymphoid malignanciesantibiomaodontogenic infection
69,565 views
20,976 downloads

Contributors:

 Jaliya moitheen.R
,
 Dr.Mijil Anand Justin
Case reportsID: BJMHR9130005Pages 48-52Open AccessOpen Access

ELECTRICAL SHOCK : AN UNCOMMON ETIOLOGY OF COLONIC PERFORATION Mohamed Anass Fehdi1, Yasser Afif1, Abdessamad Majd2,Khalid El Hattabi2 ,Mohammed Mouhaoui1

Yasser Afif, Mohamed Anass Fehdi, Abdessamad Majd, Khalid El Hattabi, Mohammed Mouhaoui

Introduction: Electrical injuries can cause deep tissue damage with life-threatening complications, yet gastrointestinal perforation remains extremely rare. We present an unusual case of colonic perforation following high-voltage electrocution. Case Presentation: A 32-year-old male sustained a high-voltage electrical shock while climbing an electric fence. He presented with diffuse abdominal pain and burn injuries at the wrist and knee. Imaging showed pneumoperitoneum. Exploratory laparotomy revealed a transverse colon laceration and an ileal perforation. Surgical repair with colostomy and wrist aponeurotomy were successfully performed. The patient recovered well with no postoperative complications. Conclusions: This case underscores the importance of maintaining high suspicion for internal visceral injuries in electrical trauma patients, regardless of superficial burn severity. Early diagnosis and prompt surgical intervention are key to favorable outcomes.

TraumaElectrisationGastrointestinal perforation
69,706 views
20,873 downloads

Contributors:

 Yasser Afif
,
 Mohamed Anass Fehdi
,
 Abdessamad Majd
,
 Khalid El Hattabi
,
 Mohammed Mouhaoui
Survey-based researchID: BJMHR9130006Pages 53-62Open AccessOpen Access

Examining Physiological Hyperarousal in the Relationship Between Insomnia and Nightmare Proneness

William E. Kelly, Ani Enriquez, Faith Yanez

Background: Nightmare proneness has been associated with insomnia beyond nightmare frequency and neuroticism. The present study examined physiological hyperarousal as a potential process contributing to this relationship. Methods: Participants were 209 adults recruited from a university participant pool and an online community sample. Participants completed self-report measures of nightmare proneness, insomnia, physiological hyperarousal, nightmare frequency, neuroticism, and trauma symptoms. Hierarchical regression and indirect-effect analyses were conducted. Results: After controlling for recruitment source, gender, nightmare frequency, neuroticism, and trauma symptoms, nightmare proneness explained an additional 6.5% of the variance in insomnia. Physiological hyperarousal accounted for an additional significant 2.2% of variance beyond nightmare proneness. Nightmare proneness showed a significant indirect association with insomnia through physiological hyperarousal. However, nightmare proneness maintained an direct association with insomnia outside physiological hyperarousal. Conclusion: Physiological hyperarousal may represent one process contributing to the relationship between nightmare proneness and insomnia but does not fully account for this association. The findings support conceptualizing nightmare proneness and physiological hyperarousal as related but non-redundant factors associated with insomnia.

Nightmare pronenessInsomniaHyperarousalNightmaresSleepNeuroticism
69,516 views
20,990 downloads

Contributors:

 William E. Kelly
,
 Ani Enriquez
,
 Faith Yanez
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