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📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

Volume 6, Issue 4 - 2019 (April 2019 Issue 4)

Volume 6 Issue 4 Cover

Issue Details:

Volume 6 Issue 4
Published:Invalid Date

Editorial: April 2019 Issue 4

Welcome to the 2019 issue of British Journal of Medical and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr Hemangi J Patel
Editor-in-Chief
British Journal of Medical and Health Research

Articles in This Issue

Showing 4 of 4 articles
Research PaperID: BJMHR0604001

Incidental Thyroid Carcinoma in Thyroidectomy Specimens and Associated Risk Factors

Bimalka Seneviratne

ABSTRACT Thyroid cancer has shown an upward trend in most parts of the world during the last few decades. In Sri Lanka thyroid malignancy is the second most common cancer in females. Incidental thyroid cancer is an unexpected malignancy seen following thyroidectomy surgery. Aim of the study was to determine the frequency of incidental thyroid carcinoma in thyroidectomy specimens submitted for presumed benign pathological disease entities such as multinodular goiter, toxic nodular goiter, chronic thyroiditis and Grave’s disease and identify the associated risk factors for the development of malignancy. A retrospective study which included 92 cases of thyroidectomy specimens from 3 specialized surgical centers. The cases with a prior fine needle aspiration cytology (FNAC) diagnosis of malignancy or suspicious of malignancy were excluded from the current study. The frequency of incidental thyroid carcinoma was 9. 78 % (09 out of 92 cases). All the cases were confirmed histologically as papillary carcinoma (p < 0.05) and the majority were < 10 mm in diameter (microcarcinoma). Incidental thyroid carcinoma showed a statistically significant association with chronic thyroiditis (p < 0.05). With limited facilities for radiological evaluation and identification of suspicious nodules in the growing numbers of patients with multinodular goiters, the risk of missing incidental thyroid carcinoma especially microcarcinomas, will continue to lurch in the same manner. Keywords: Incidental thyroid carcinoma, thyroidectomy, multinodular goiter

Incidental thyroid carcinomathyroidectomymultinodular goiter
34,213 views
10,242 downloads
DOI:
10.46624/bjmhr.2019.v6.i04.001

Contributors:

 Bimalka Seneviratne
Research PaperID: BJMHR0604002

Correlation of diagnostic accuracy of ELISA and Rapid Test Reader used in Immunochromatographic Assay

Kathiravan V, Swaminathan S

Background: Early and accurate detection of HIV infection is essential for patient management and disease control. The primary methodology for HIV testing has shifted from enzyme linked immunosorbent assay (ELISA) to rapid diagnostic tests in recent years, especially in resource limited settings. Purpose: To correlate two new commercial serologic tests for HIV (ALTA rapid test reader RTR-1, CTK Biotech and HIV ELISA; GenscreenTM ULTRA HIV Ag-Ab). Study design: The sensitivity and specificity of the HIV tests were compared using unknown HIV status of 955 specimens. Results: The two different assays showed excellent sensitivity in the diagnosis of HIV infection (100%). Specificity in RTR was (100%), whereas it is (98.3%) in ELISA which indicates, ELISA given (1.7%) false positive results. Conclusions: Rapid test reader can be useful in the effective and economical screening method for HIV infection. However, rapid test reader is not a substitute for ELISA method

HIV diagnosisELISARapid diagnostic test reader
34,244 views
10,431 downloads
DOI:
10.46624/bjmhr.2019.v6.i04.002

Contributors:

 Kathiravan V
,
 Swaminathan S
Research PaperID: BJMHR0604003

Epidermolysis Bullosa Simplex: A Case Report

siddaruda m biradar, siddaruda m biradar

Epidermolysis bullosa (EB) is a rare and genetically determined skin fragility disorders. It has many genetic and symptomatic variations, but all share the prominent symptom of extremely fragile skin that blisters and tears from minor friction to trauma. It is always painful, often pervasive and debilitating. Its affects 1 out of every 50,000 live births and those born with it are often called ‘Butterfly Children’ that is delicate and fragile as butterfly wings. As there is no standard protocol for the treatment of EB and clinic features remains multiple and varied, hence treatment for the disease remains a major challenge. Therefore the current therapy focuses on prevention of progression of disease, nutritional support, bandage dressing and psychological support to the parents/guardians. Hence the platform provides this is a scope for discovery and development new drugs/treatment strategic plans for the treatment of Eidermolysis bullosa in order to recede the innocent babies’ agony.

Epidermolysis bullosaEpidermolysis bullosa simplexMultidisciplinary treatmentScope for Gene therapy.
34,523 views
10,455 downloads
DOI:
10.46624/bjmhr.2019.v6.i04.003

Contributors:

 siddaruda m biradar
,
 siddaruda m biradar
Research PaperID: BJMHR0604004

Cyanotoxin Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis

Alireza . Heidari, Jennifer . Esposito, Angela . Caissutti

ABSTRACT Cyanotoxins are toxins produced by bacteria called cyanobacteria (also known as blue–green algae). Cyanobacteria are found almost everywhere, but particularly in lakes and in the ocean where, under high concentration of phosphorus conditions, they reproduce exponentially to form blooms. Blooming cyanobacteria can produce cyanotoxins in such concentrations that they poison and even kill animals and humans. Cyanotoxins can also accumulate in other animals such as fish and shellfish, and cause poisonings such as shellfish poisoning. Parameters such as FT¬–IR and Raman vibrational wavelengths and intensities for single crystal Cyanotoxin are calculated using density functional theory and were compared with empirical results. The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bounds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Cyanotoxin is performed based on theoretical simulation and FT–IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations. Keywords: Vibronic Structure, Vibrational Spectra Analysis, Density Functional Theory (DFT), Cyanotoxin, Non–Focal Functions of Becke, Correlation Functions of Lee–Yang–Parr, Time–Resolved Absorption and Resonance, FT–IR and Raman Biospectroscopy

Vibronic StructureVibrational Spectra AnalysisDensity Functional Theory (DFT)CyanotoxinNon–Focal Functions of BeckeCorrelation Functions of Lee–Yang–Parr+2 more
34,477 views
10,406 downloads
DOI:
10.46624/bjmhr.2019.v6.i04.004

Contributors:

 Alireza . Heidari
,
 Jennifer . Esposito
,
 Angela . Caissutti

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