e-ISSN: 2394-2967
logo

British Journal of Medical and Health Research

LoginTrack

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

Volume 4, Issue 12 - 2017 (December 2017 Issue 12)

Volume 4 Issue 12 Cover

Issue Details:

Volume 4 Issue 12
Published:Invalid Date

Editorial: December 2017 Issue 12

Welcome to the 2017 issue of British Journal of Medical and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr Hemangi J Patel
Editor-in-Chief
British Journal of Medical and Health Research

Articles in This Issue

Showing 7 of 7 articles
Research PaperID: BJMHR0412001

Purification and Characterization of Novel Peroxidase Enzyme from wild white Rot Fungi- A Review

Astha . Tripathi, Neha . Thakur

Wood-decomposing fungi colonizing dead or dying tree trunks and stumps utilize cellulose while modifying the hemicellulose and lignin constituents cause either brown-rot or more commonly, white-rot via the utilization of hemicellulose and cellulose during the degradation of lignin. White Rot fungi (WRF) produce different types of enzymes that are characterized by different or specialized group of Peroxidases. Versatile Peroxidase (syn. Hybrid peroxidase, manganese- lignin peroxidase) is a new ligninolytic enzyme, combining catalytic properties of manganese peroxidase, oxidation of Mn (II), lignin peroxidase (Mn-independent oxidation of non-phenol aromatic compounds) and plant peroxidase (oxidation of hydroquinone and substituted phenols). The ligninolytic enzymes of white-rot fungi have broad substrate specificity and have been implicated in the transformation and mineralization of organopollutants with structural similarities to lignin.

Rot FungiLigninolytic enzyme
27,610 views
8,271 downloads

Contributors:

 Astha . Tripathi
,
 Neha . Thakur
Research PaperID: BJMHR0412002

Tobacco Cessation Counseling Interventions: An update on Current Approaches

K. A. Kamala, S . Sankethguddad, Ajay G. Nayak, Abhijeet R. Sanade

Tobacco smoking is globally far more widespread than use of any other form of substance abuse. Its use remains the leading preventable cause of morbidity and mortality, each year causing more than 6 million deaths globally. The World Health Organization estimates there are 1.3 billion smokers worldwide and each year 5 million smokers die because of tobacco-related diseases. Data suggest that up to 70% of current smokers want to quit and 40% attempt to do so each year. Timely intervention in smoking cessation not only reduces the risk of major disease, but also modifies the clinical course and outcome of certain diseases. There are various pharmacological and non pharmacological measures available which need to be implemented properly and timely. Strategies for assisting smoking cessation include non-pharmacological therapies to enhance motivation and to support attempts to quit and pharmacological intervention to reduce nicotine reinforcement and withdrawal from nicotine. The pharmacological interventions include nicotine replacement therapy (NRT) and antidepressants. Non-pharmacologic interventions includes behavioral interventions, cognitive behavioral therapy (CBT), individual or group consoling, telephone counseling and self –help counseling. The present review aims at analyzing the current knowledge of various smoking cessation strategies

tobacco addictionpharmacologicalno pharmacologicalvaccines.
27,988 views
8,447 downloads

Contributors:

 K. A. Kamala
,
 S . Sankethguddad
,
 Ajay G. Nayak
,
 Abhijeet R. Sanade
Research PaperID: BJMHR0412003

Importance of follow up in the diagnosis of Overlap Myositis – A short communication

Ashwin Kulkarni, ASHWIN KULKARNI, Anika Nair, Vishwanath K, Anil Kumar T

Abstract- Overlap myositis are the group of conditions characterized by varying degree of muscle weakness in an underlying connective tissue disorder like Systemic lupus erythematosis, Systemic sclerosis and Rheumatoid arthritis . Overlap myositis presents subacutely and muscle weakness may not be present at the time of presentation of the underlying connective tissue disease. Many cases tend to have vague clinical features which causes the diagnosis more difficult. The myositis tends to be diagnosed during follow up of these diseases. Here we present three cases in which patients developed muscle weakness later then the initial presentation of the primary disease. Hence we emphasize the importance of regular follow up of the patients having connective tissue disorder and to specifically enquire regarding muscle pain and weakness. This will help in the early diagnosis of overlap myositis.

- Overlap myositisFollow upSystemic sclerosisMuscle biopsy
27,881 views
8,383 downloads

Contributors:

 Ashwin Kulkarni
,
 ASHWIN KULKARNI
,
 Anika Nair
,
 Vishwanath K
,
 Anil Kumar T
Research PaperID: BJMHR0412004

The impact of education ( or lack of it ) on awareness of thyroid and its disorders in the community.

Vasudevan Devanathan, Deepika Vasudevan

Background: Thyroid disorders are one of the most common health issues worldwide including India. However, many people, even today, are not aware about the location of the thyroid gland and its function. As impaired function of the thyroid gland has a profound impact on health, it is imperative to gauge the existing level of awareness in society about thyroid gland and its disorders, in order to ascertain what additional steps need to be taken. Moreover there is paucity of studies on awareness of thyroid diseases among the general population. The present study determines the level of awareness in the community about the thyroid gland and its functions and to assess impact of level of education on awareness. Materials and Methods: A cross sectional study was conducted on randomly selected people in two different residential areas of Chennai city, Tamilnadu. Total of 132 people were evaluated with a questionnaire during the period September 2016 to March 2017. Result: In the present study, out of 132 participants only 93 (70.5 %) knew that thyroid is a normal gland present in the neck. With respect to symptoms only 58 (43.9%) knew about one or more symptoms of hyper or hypothyroidism of which 35 (26.5%) were graduates, 6 (4.5%) were educated upto secondary school and 17 (12.9%) upto higher secondary school. Among the participants 87 (65.9 %) were aware about iodised salt but the connection between iodised salt and hypothyroidism was not known. Conclusion : This study shows that people lack basic knowledge about thyroid disorders despite their level of education. Promotion of awareness should be undertaken at all levels. Appropriate use of social and other media should be considered to make the community, health workers, and policy makers aware of the prevalence of thyroid disorders and to clarify commonly held beliefs so that incidence of hypothyroidism in the country can be decreased and eventually prevented.

Thyroid glandHypothyroidismIodised saltPublic awareness
28,025 views
8,496 downloads

Contributors:

 Vasudevan Devanathan
,
 Deepika Vasudevan
Research PaperID: BJMHR0412005

SERUM ANGIOTENSIN CONVERTING ENZYME LEVELS IN NIGERIAN TYPE 2 DIABETIC PATIENTS IN PORT HARCOURT

Asuquo Bassey Ene, Henry Chima Okpara

BACKGROUND: Angiotensin converting enzyme (ACE) regulates blood pressure and its increased level has been implicated in the microvascular and macrovascular complications of diabetes mellitus. These complications arise by chronic hyperglycaemia progressively causing formation of advanced glycation end products generating free radicals that lead to tissue damage. OBJECTIVE: The aim of the study was to assess the serum level of angiotensin converting enzyme in adults with type 2 diabetes mellitus. METHOD: A cross-sectional study conducted on 120 confirmed cases of adult type 2 diabetes patients who were on hypoglycaemic medication (but not taking ACE inhibitors) and 120 apparently healthy age-matched control subjects. Blood was collected in plain and lithium heparin bottles (for ACE and other analytes) respectively. Serum ACE levels were estimated with Eton Bioscience ELISA kits. Plasma electrolytes were analysed with ion selective electrodes while plasma urea and creatinine were estimated with Randox test kits, to assess renal function. Data generated was analysed with SPSS version 20.0. RESULTS: The mean ACE level in diabetic subjects was 25.61 ± 0.63 IU/L, and 23.69 ± 0.84 IU/L for control subjects (p = 0.01). While there was difference in ACE levels among the male diabetic subjects and control subjects (p = 0.04), there was no such difference among the females (P = 0.10). There was no association between the ACE levels and the parameters of renal function. CONCLUSION: The study found out that serum ACE was higher in diabetes male subjects. Despite the progressive effect of diabetes on renal function, the enzyme level was not affected by the duration of diabetes.

Angiotensin converting enzymetype 2 diabetes mellitusNigeria
28,006 views
8,480 downloads

Contributors:

 Asuquo Bassey Ene
,
 Henry Chima Okpara
Research PaperID: BJMHR0412006

A Case Report of Blood Pressure Variation in Diabetes

B C Kalmath

Blood pressure is a biological variable that varies with time. A series of factors linked to daily activities and independent neurohormonal mechanisms cause blood pressure to vary significantly within the 24 hours of the day: it increases during physical activity and decreases considerably following acute exercise (post-exercise hypotension); it increases in conditions of physical or emotional distress and tends to decrease after meals and during sleep.1 Blood pressure variation throughout the sleep-wake cycle is well known, with lower values observed during night time sleep than in daytime wakefulness. The advent of non-invasive methods to measure blood pressure for 24 hours such as ambulatory blood pressure monitoring (ABPM) shed more light onto the behaviour of blood pressure. Changes in blood pressure during sleep have also been associated with increased risk of cardiovascular and renal disease in the long term: it is the classical description of inadequate or absent drops in blood pressure during sleep seen in attenuated dippers and non-dippers, respectively, associated with left ventricular hypertrophy, hypertensive retinopathy, and proteinuria.2 A mathematical formula based on the different blood pressure levels observed in subperiods of the sleep-wake cycle was recently proposed to estimate the early morning rise in blood pressure. Pronounced rises in blood pressure during this time of the day (“early morning surge”) have also been used to independently predict mean 24-hour, wake, and sleep blood pressure and the Blood pressure variability3

Blood pressureDiabetes
28,533 views
8,481 downloads

Contributors:

 B C Kalmath
Research PaperID: BJMHR0412007

The next big thing: A case report on Blood Pressure Variation encountered in my clinic

Johann . Christopher

The role of high Blood Pressure levels on target organ damage and the protective effects of antihypertensive therapy have been extensively established in clinical practice [1]. Mortality from ischemic heart disease and stroke doubles every increment in 20 and 10 mmHg of systolic and diastolic blood pressure [1]. Nowadays, besides usual blood pressure other parameters contribute to TOD in hypertensive patients [2]. Blood pressure is a constant variable and it shows marked spontaneous oscillations over short-term (minutes to days) and long-term (month) periods [3]. Early reports from animal models of cardiovascular variability have clearly demonstrated the relationship between excessive fluctuation in blood pressure values and the development of target organ damage [4]. The initial hypothesis was further corroborated by clinical studies in hypertensive subjects showing that the assessment and quantification of Blood Pressure Variability (BPV) is of physio-pathological and prognostic importance [5]. In recent years, many preclinical and clinical studies have clearly identified the contribution of BPV to the cardiovascular complications associated with hypertension [6]. Moreover, preliminary data from retrospective analysis of clinical trials suggest that attenuation of BPV by antihypertensive agents contribute in the prevention of major cardiovascular events in hypertensive patients [7]. Considering the recent advances in the knowledge of the pathological role and clinical significance of BPV in cardiovascular diseases, the present case illustrates the Blood Pressure Variation in a routine OPD setting.

Blood PressureAnimal models
28,284 views
8,473 downloads

Contributors:

 Johann . Christopher

Related Issues

Volume 13, Issue 1

2026 • 2 articles

Volume 12, Issue 12

2025 • 2 articles

Volume 12, Issue 11

2025 • 2 articles

Volume 12, Issue 10

2025 • 2 articles