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📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

Volume 4, Issue 1 - 2017 (January 2017 Issue 1)

Volume 4 Issue 1 Cover

Issue Details:

Volume 4 Issue 1
Published:Invalid Date

Editorial: January 2017 Issue 1

Welcome to the 2017 issue of British Journal of Medical and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr Hemangi J Patel
Editor-in-Chief
British Journal of Medical and Health Research

Articles in This Issue

Showing 6 of 6 articles
Research PaperID: BJMHR0401001

Clinical Usefulness of LDH In Various Tumors – An Update

Swaminathan Selvanayagam, Elanthendral . ., Rajeswari . S, Masood . Ikram

LDH, one of the earliest marker still being used along with troponins in the diagnosis of acute myocardial infarction is now emerging as an important marker in a wide range of cancers. Recently LDH and its isoenzymes have been extensively studied in the detection and its prognostic role in common tumors such as colorectal, breast, ovarian, prostate, liver and various other metastases. LDH levels have been correlated with CEA, CA 15.3, CA 125,CA19.9 and Hodgkin’s lymphomas. Further, isoenzymes of LDH are being studied extensively and each isoenzyme was found to be specific for a particular cancer. LDH has been linked to intracellular enzymes through damaged cells in apotoposis and deregulation. Studies suggest that inhibiting LDH activity may lead to possible anticancer treatment. The objective of this review article is to present the outcome of various research findings during the last two decades and to make awareness among research scholars to undertake further research to establish the exact clinical role of LDH in each type of cancer.

TumorLDHCEACA 125HCCCA 15.3
19,359 views
5,788 downloads

Contributors:

 Swaminathan Selvanayagam
,
 Elanthendral . .
,
 Rajeswari . S
,
 Masood . Ikram
Research PaperID: BJMHR0401002

A Review On the Occurrence, Causative Factors and Pattern Of Malnutrition In Patients With Chronic Obstructive Pulmonary Disease

Asna Urooj, Chandan Vinay Srigiripura

Chronic obstructive pulmonary disease (COPD) is a disease of the respiratory system characterised by extra pulmonary manifestations that includes nutritional depletion, which is known to have negative consequences on morbidity and mortality. Chronic malnutrition results in reduced lung and respiratory muscle function secondary to loss of lean body mass, multiple nutrient deficiencies and cachexia when chronic in nature. A literature review was performed on the prevalence and trend of malnutrition, reported in COPD patients. Increased resting energy expenditure, thermic response to food, early satiety, increased pro inflammatory cytokines are known to lead to loss of appetite, weight loss and cachexia on a long term. Under nutrition among various study populations is reported between 20-70% and cachexia in 27-33% of subjects with COPD. Malnourished individuals are exposed to higher risk of mortality, morbidity and poor prognosis by the reduced pulmonary function and risk of infections due to the loss of fat free mass, skeletal muscle strength, lower immune function secondary to malnutrition. Pre-existing oxidative stress can be further worsened by deficits in micronutrient intakes. Anthropometric assessment including fat free mass is important in evaluating nutritional depletion as some COPD patients may lose fat free mass without any alterations in fat mass. Thus, COPD patients can suffer from malnutrition, further aggravated by the severity of symptoms, biochemical alterations and severity of disease. Further, undernutrition can negatively affect the prognosis necessitating a thorough assessment of body composition along with somatic status among patients losing weight and those with a history of weight loss.

CachexiaFat free massMalnutritionNutritional depletionOxidative stress.
19,370 views
5,931 downloads

Contributors:

 Asna Urooj
,
 Chandan Vinay Srigiripura
Research PaperID: BJMHR0401003

99mTc Pertechnetate Thyroid Uptake and Scintigraphy: Standardization in Euthyroid Subjects

Md. Monirul Haque, M. C. Mia, M. S. Hossain, M. S. Reza

Thyroid uptake and scintigraphy at 20 minutes of intravenously administered 99mTc sodium pertechnetate were studied on 50 euthyroid and healthy Bangladeshi individuals. The aim of this study was to standardize a simple and fast methodology for performing thyroid uptake and scintigraphy and to determine the euthyroidism range for 99mTc pertechnetate uptake. The laboratory assessment of thyroid function consisted of serum dosages of ultrasensitive thyroxin and thyrotropin. The images were obtained on a computerized scintillation camera equipped with a low-energy high-resolution parallel-hole collimator. The present study observed that the assessment of thyroid structure and function using 99mTc-pertechnetate is a simple, fast and efficient method. The observed thyroid uptake range for euthyroid individuals are from 2.1 to 4.1% of the injected dose.

Thyroid uptakeScintigraphy99mTc-pertechnetateStandardizationEuthyroidism.
19,543 views
6,005 downloads

Contributors:

 Md. Monirul Haque
,
 M. C. Mia
,
 M. S. Hossain
,
 M. S. Reza
Research PaperID: BJMHR0401004

SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME NEW PYRIMIDINE DERIVATIVES FROM CHALCONES

hareesh divadari, vijay srinivas pothula

Chalcones have been reported to present various biological activities such as anti-inflammatory, antioxidant, antitubercular, antibacterial activities. It is a basic moiety of many heterocyclic systems containing oxygen, sulphur and nitrogen. Nitrogen containing heterocyclic derivatives synthesized from Chalcones have exhibited anti-inflammatory, anticancer and antimicrobial activities. An attempt has been made to synthesize Chalcones by the reaction of 3-acetyl-2,5-dimethylfuran with various aromatic and heteroaromatic aldehydes. Further, Chalcones derivatives were cyclised to pyrimidine analogs by using guanidine hydrochloride. The newly synthesized pyrimidine derivatives have been characterized by IR, 1HNMR, 13CNMR, Mass spectra and elemental analysis and evaluated for their anti-inflammatory, anticancer, antifungal and antibacterial activities. It was found that 2-amino pyrimidine analog bearing 4-chloro substitution on phenyl ring has exhibited excellent anticancer activity at lowest concentration in the series moreover it has also exhibited good anti-inflammatory and antibacterial activities

Chalconespyrimidineanticancer activityantifungal activityantibacterial activity.
19,750 views
6,025 downloads

Contributors:

 hareesh divadari
,
 vijay srinivas pothula
Research PaperID: BJMHR0401005

THE IMPACT OF THE AWARENESS OF THE PARENTS ON THE PROPHYLAXIS OF FLAT-FOOTED CHILDREN

PLAMEN DIMITROV DIMITROV, Mariyana Mihailova Krasteva, Silviya Ivanova Filkova

Abstract Introduction Until 5 years of age, the kids have physiological flat-feet. It’s from a great sign if I can to conduct a prophylaxis starting from young age continuing throughout the entire life. Purpose: To research the impact of parent’s awareness on the prophylaxis off l at-feet in children. Methods and materials: The survey was carried out in June 2016. The survey included 12 closed questions, directed towards exploring the awareness if the parents regarding the condition flat-feet, its diagnostics, prophylaxis and its impact on the general health of the children. In the research participated 59 parents of children between the age of 5 and 17. The gathered data were analyzed using the statistical software package IBM SPSS for Windows, v. 19.0. Results: The majority of the surveyed parents - 57,6% (n=34) haven’t taken their kid to the GP for a prophylactic examination. In 22% (n=13) of the examined children flat-feet have been found. According to 13,6%(n=8) of the parents that is very important for their child’s health, 6,8%(n=4) stated it’s relatively important and 1,7% (n=1) find it not important. The vast majority 89,8% of the respondents are interested in receiving more information, Conclusions: The parents claim that they’re familiar with the condition flat-feet, but when analyzing their responses in our survey, we can conclude that their knowledge should be broadened.

flat-footedprophylaxisawarenesschildren
19,773 views
6,010 downloads

Contributors:

 PLAMEN DIMITROV DIMITROV
,
 Mariyana Mihailova Krasteva
,
 Silviya Ivanova Filkova
Research PaperID: BJMHR0401006

Strategic Memory Alzheimer’s Rehabilitation Training (SMART): Cognitive Intervention for Amnestic-type Mild Cognitive Impairment (MCI)

Dr. John DenBoer

Dementia is a growing world-wide phenomenon, impacting more than six million people in the United States. Despite its high projected prevalence, it is a significantly under-represented phenomena, with estimates ranging from 15-25% of the general population. The effect of the aging of the population and significant increase in life expectancy has combined to catapult dementia into the range of one of most alarming healthcare problems. The SMART Memory Program is a cognitive intervention designed to help promote the reduction of mild cognitive impairment (MCI) and early-stage dementia. Although it has been found useful in all forms of dementia, it is particularly useful in amnestic-type MCI. A longitudinal study examined 356 clients (220 females, all amnestic-type MCI) across an approximate two-year span. Results revealed an improvement of approximately 3 MoCA points at the conclusion of a program session. Particular improvements were noted in delayed recall. These results were found to be particularly beneficial secondary to the advent of the Kirtan Kriya methodology.

SMARTmild cognitive impairmentdementiaAlzheimer’s diseasecognitive preventioncognitive intervention
19,857 views
6,085 downloads

Contributors:

 Dr. John DenBoer

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