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British Journal of Medical and Health Research

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

📢 Latest Update: Call for Papers: Special Issue on Medical and Health Research – Submit to British Journal (BJMHR) by March 31, 2026

Volume 1, Issue 1 - 2014 (October 2014 Issue 1)

Volume 1 Issue 1 Cover

Issue Details:

Volume 1 Issue 1
Published:Invalid Date

Editorial: October 2014 Issue 1

Welcome to the 2014 issue of British Journal of Medical and Health Research. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr Hemangi J Patel
Editor-in-Chief
British Journal of Medical and Health Research

Articles in This Issue

Showing 5 of 5 articles
Research PaperID: BJMHR0101001

Concepts of Manas (~mind): An Insight from VaiseshikaDarshana and Ayurveda

Hetal D Amin, Rohit Sharma

Various means of valid or right knowledge have been discussed at its highest length are described in Vaiseshika Darshana. The concept of this philosophical system has enormously used in Ayurveda; off course they formed the fundamental base for acquiring the main objectives of Ayurveda. It is very necessary for an Ayurvedic scholar to screen the philosophical views which are present in Ayurvedic classics for the better understanding of the science in all aspects.The concept of Manas (~mind) is commonly seen as one key issue in Indian philosophy of mind. Therefore, here, an attempt has been made to highlight the concepts of Manas in Vaiseshika Darshana under the view of Ayurvedic texts.

AyurvedaManasMindVaiseshikaDarshanamemory.
1,302 views
467 downloads

Contributors:

 Hetal D Amin
,
 Rohit Sharma
Research PaperID: BJMHR0101002

Analytical Method Development and Validation for Simultaneous Estimation of Sildenafil Citrate and Dapoxetine Hydrochloride In Pharmaceutical Dosage Form By RP-HPLC

Jitendra S PATEL, Tejas Thakar, Minakshi Dhoru, Sandip Dholakia, Madhabhai M Patel

Sildenafil Citrate (50mg) and Dapoxetine Hydrochloride (30mg) in combination used for the treatment of Premature ejaculation and Erectile dysfunction. Market survey and literature review revealed that there were so many methods available for single Sildenafil Citrate and DapoxetineHydrocloride and UV spectrophotometric method by absorbance correction method and simultaneous equation method (vierodt’s method) are available in 2013 . So it was thought of intrest to develop and validate simple, accurate, sensitive and rapid new UV spectrophotometric and RP-HPLC method for simultaneous estimation of Sildenafil Citrate and Dapoxetine Hydrochloride in Pharmaceutical dosage form. In RP-HPLC method, chromatographic separation was achieved on Hypersil ODS C18 (250mm x 4.6 mm id, 5m particle size) column using Methanol:Water buffer at pH 3 (pH of buffer was adjusted to 3.0 with dilute 0.5% ortho-phoshporic acid) (95:05 v/v) as mobile phase. Detection was carried out at 225 nm.

Sildenafil CitrateDapoxetine HydrochlorideRP-HPLCValidation.
1,743 views
389 downloads

Contributors:

 Jitendra S PATEL
,
 Tejas Thakar
,
 Minakshi Dhoru
,
 Sandip Dholakia
,
 Madhabhai M Patel
Research PaperID: BJMHR0101003

Occurring of stammering in the population of Sheringal, Dir upper, Khyber Pakhtunkhwa, Pakistan

farzana Perveen, Inayat Ul Islam

Stammering is a developmental disorder, which may adversely affect the individual on many functional and emotional levels, such as anxiety, shame, anger, as well as speech-avoidant behaviors in human, Homo sapiens L. According to present study, the occurring of stammering was determined in the population of Sheringal, Khyber Pakhtunkhwa, Pakistan during June 2013-August 2014. The questionnaires having all information about stammering were distributed among (n=200) the people of Sheringal by random method. Daramdala, Doki, Guryaal, Samang, Shahoor and Sia-Sheringal were the 6 quadrates of the study area. Stammering was the highest in middle class (55%) and the lost in lower class (8%). The major stammering occurring age was 6-12 years (28%). Stammerers suffered different disease, however, the highest occurring disease was epilepsy (8%), however, the lowest was heart disease (1%). Numbers of stammerers found were minimum, 1 stammerer/ family out of 39 families and maximum, 3 stammerers/ family out of 4 families (N=47). Stammerers have been facing different obstacles, however, maximum obstacles were tongue pain (14.5%) and minimum were lungs pain (6%). The maximum stammerers were un-employee (63%). Commonly stammering was occurring during pre-school and school life. The present research will be useful to educate the people about stammering. The gender and congenital bass’s investigations are necessary for further research.

BlockingdepressionoccurringstammeringSheringal.
1,738 views
471 downloads

Contributors:

 farzana Perveen
,
 Inayat Ul Islam
Research PaperID: BJMHR0101004

Estimation of Vitamin D among Diabetic, Hypertensive, and Obese Sudanese Individuals

AbdElkarim A Abdrabo, Razan M Elabass

This study was carried out to analyze and compare the concentration of vitamin D in the metabolic syndrome's individuals (diabetics, hypertensive, obese) with normal individuals. The study involved a group of healthy individuals as controls (N = 95, age range was 18-68 years) matched with a test group of metabolic syndrome's individuals (N = 65, age range was 11-61years). The groups contain 130 female and 130 male. The serum 25-OH vitamin D level was estimated using ELISA method. Appropriate statistical tests were used to assess significant difference in the means of the estimated concentrations between patients and the control group. The mean serum level of vitamin D significantly lower in metabolic syndrome's groups (diabetics: 20.32±12.46 ng/ml, hypertensive: 24.50±10.69 ng/ml, obese: 21.60±6.75 ng/ml) when compared with control group (37.52±11.14 ng/ml), P< 0.000. It may be useful to do early screening and treatment of hypovitaminosis D in metabolic syndrome's individuals to prevent the vitamin D deficiency and its complications.

Metabolic syndromevitamin Ddiabeteshypertensionobesity
1,539 views
601 downloads

Contributors:

 AbdElkarim A Abdrabo
,
 Razan M Elabass
Research PaperID: BJMHR0101005

To Study the Effect of Hydroalcoholic Dissolution Media for Integrity of Sustained Release Polymer

Hemangi PATEL, NIkunjkumar Patel

In July 2005, the FDA issued an alert for healthcare professionals regarding dissolution media effects on drug release from a SR dosage form not involving a hydrophilic matrix, i.e., alcohol-Palladone interaction1. Hence, the aim of present works was to check the effect of Hydro alcoholic dissolution media in sustained release polymer and investigate the influence of hydro-alcoholic media on drug release for metoprolol Succinate sustained release tablets. Metoprolol succinate is a drug used for Hypertension and it is suitable drug candidate for extended release due to its short Half-life. Combination of HPMC K4M and HPMC K100M, Carbopol 934 P, Chitosan, HPMC K100 M: Ethyl Cellulose (4:1), Sodium-Carboxyl Methyl Cellulose were used as a polymer matrix to control the release of Metoprolol succinate up to 12 hrs. The Sustained release tablets of Metoprolol succinate were prepared by Wet granulation method. All the tablets were evaluated for the Pre-compression and post Compression Parameter. In-vitro dissolution study was done in Normal Dissolution Media, Phosphate Buffer pH 6.8 and also in 10 %, 20 %, 30 % and 40% v/v ethanol solutions for up to 12 hrs. All HPMC, Chitosan, Sodium-CMC preparation did not fail in hydro-alcoholic media, while Carbopol 934 P preparation show highest differences compare to all other. The highest dissolution was found to be more than 80 % in 12 hours for 40 % v/v ethanol solution in Carbopol 934 P ,which was not comply with standard range of drug release by USFDA and show dose dumping of Formulation. Kinetic model application confirmed that the release of Metoprolol succinate follows zero order as well as Korsmeyer-Peppas model. From these studies it was concluded that Carbopol 934 P formulation indicated highest signs of a potential dose dumping compare with other formulation.

Dose dumpingSustained Release PolymerHydroalcoholic Dissolution Media.
1,737 views
663 downloads

Contributors:

 Hemangi PATEL
,
 NIkunjkumar Patel