Parul Dutta

ABSTRACT Brown tumor also known as osteitis fibrosa cystica generalisata or Von Recklinghausen’s disease of bone, is a metabolic bone disease that develops in primary, secondary or tertiary hyperparathyroidism. Brown tumors can occur in any location but are most common in the ribs, clavicle and pelvis. The reported prevalence of brown tumors is 3% in primary hyperparathyroidism and can occur in mandible very rarely [1]. We describe an unusual case of primary hyperparathyroidism in a 30-year-old female patient presenting with mandibular brown tumor as the first clinical manifestation. It should be differentiated from other true giant cell tumors of bone. Keywords: Brown tumour, primary hyperparathyroidism, parathyroid adenoma, mandible.

Stroke is the third most common cause of death worldwide. There is a close relationship between ischemic cerebral vascular accidents and carotid artery stenosis due to various causes. Imaging of the extra cranial portion of the carotid arteries plays a important role in diagnosing various carotid artery diseases including atherosclerosis, which in turn can predict atherosclerosis of the entire vascular system of the body. Atherosclerosis of intracranial arteries is a well-recognized cause of ischemic stroke in Asians, and extracranial carotid artery disease is more often seen in western countries. Due to its wide availability, USG can be used as an important diagnostic tool for proper evaluation of patients of cerebrovascular accident in emergency setting. This paper aims to discuss the results of our hospital based cross sectional study on the various morphological and physiological changes taking place in the extracranial portion of carotid arteries as an underlying pathological process in patients presenting with signs and symptoms of cerebrovascular insufficiency. Increased IMT, presence of plaque, and evaluation of plaque characteristics such as types, surface, sites, morphology, etc. can be useful to estimate the predictable risk for a cerebrovascular event in the future. Echolucency of plaque, intraplaque hemorrhage, and plaque ulceration are plaque morphologies, that have been found to be associated with increased risk of Ischaemic stroke. In addition to that, doppler velocity parameters of the stenotic segments can provide information about the resultant changes in the hemodynamics.