CORRELATION BETWEEN SERUM URIC ACID IN PRE DIABETICS AND DIABETICS:A PROSPECTIVE OBSERVATIONAL STUDY

Objectives: To determine the level of serum uric acid level in diabetics and pre diabetics individuals. To compare the level of serum uric acid , FPG , HBA1C in pre diabetics and diabetics. Results: There was a significant relation between prediabetics who were younger in age compared to diabetics (almost a decade younger). The gender distribution was identical between the two groups. 53% had complaint <1 year.39% had isolated HTN; 9% had IHD whereas 19% had both. The diabetics had HbA1c significantly higher than prediabetics. Although proportionately more prediabetics had raised creatinine levels, but the difference was not significant. The difference of mean uric acid wrt HbA1c was not significant, although people with lower HbA1c values had a higher uric acid levels. The difference was not significant wrt uric acid levels with FBS values in prediabetics. The difference was not significant, although people with lower PPBS had higher uric acid levels in prediabetics. There was a significant relation of lower uric acid mean values for people with elevated HbA1c over 7g% amongst diabetics. There was no significant relation, although mean uric acid levels were raised for people with FBS<110 amongst diabetics. There was no significant relation but uric acid levels were higher in people with PPBS <140 amongst diabetics Conclusion: Younger age in India is predisposed to prediabetes and diabetes. Often patients are silent, without symptoms and detected only by investigations, so investigations for prediabetes and diabetes should be mandatorily routine. Lower uric acid levels have correlation with impaired glycemic control and should be part of check ups for metabolic syndromes. Hypertension and heart disease commonly coexist with diabetes and should be tackled together. Uric acid monitoring should have a role in guiding glycemic goals