Comparative study of combined Foley Bulb and Vaginal Misoprostol with Vaginal Misoprostol alone for cervical ripening and Induction of Labour

To study efficacy of combination of foley bulb and vaginal misoprostol in comparison to vaginal misoprostol alone for cervical ripening and induction of labour. A prospective randomized study was conducted on 150 patients with term singleton pregnancy admitted for induction of labour. Seventy five patients were induced with both foley bulb and vaginal misoprostol and another 75 were given vaginal misoprostol alone for induction of labour. Both groups were then compared with respect to change in bishop score, induction to active phase of labour interval, induction delivery interval, duration of labour,maternal complications and neonatal outcomes. Data was analyzed using chi square test and student t test.: Of two groups, change in bishop score after 4 hours of induction of labour was more in combination group. Induction delivery interval was shorter in combination group;11.76±5.89 hours than misoprostol group; 14.54±7.32hours;p=0.018. Total duration of labour was less in combination group(6.08±2.88 hours) than misoprostol group(8.20±3.62 hours);p=0.000. The results were more significant in nulliparous women. Change in bishop score is more and duration of labour and induction delivery interval becomes shorter when induction is done with combination of foley bulb and vaginal misoprostol instead of vaginal misoprostol alone. So, all nulliparous women with poor bishop should be offered induction with combination of foley bulb and vaginal misoprostol.