Granulomatosis with polyangiitis (Wegener's disease) in a black patient revealed by neuro-ophthalmological involvement

Granulomatosis with polyangiitis (GPA) is a systemic vasculitis. The authors report a case of Wegener's disease in a black patient revealed by neuro-ophthalmological involvement. A 38-year-old patient was seen in consultation for dizziness and headaches. In 2007, he presented with uveitis and retinal detachment, resulting in blindness in his right eye. Eleven years later, the condition recurred in the contralateral eye, although less severely. The neurological examination in December 2024 was normal. The ophthalmological examination noted sequelae lesions. Angio-MRI noted non-specific hypersignals in the white matter. The anti-polynuclear cytoplasm antibody test was positive for c-ANCA with anti-proteinase 3 specificity.Wegener's granulomatosis is a rare condition in our work context. It is a chronic, recurrent condition that is severe in both vital and functional terms.