Cardiovascular diseases comprise the most prevalent serious disorders in industrialized nation and are rapidly growing problem in developing nations. The percentage of all deaths secondary to cardiovascular disease is higher among women i.e 43% than among men i.e 37%.1 Atherosclerosis remains the major cause of cardiovascular disorders. In Ayurveda there is very brief description of Hridroga, but based on its presentation we can correlate Vataj Hridroga with Coronary Artery Disease (CAD). This study highlights the potential efficacy of herbo-mineral formulations in the management of Vataj Hridroga. To analyse the effect Ayurvedic management of Coronary Artery Disease (CAD) with Jawahar Mohra, Khamira Gawzaban Ambari and Pushkargugglu Vati. This was a single case study. In this study a diagnosed patient of Coronary Artery Disease (CAD) was taken. There was significant improvement in the clinical sign and symptoms.