ABSTRACT The main objective of this present work is, to test the antimicrobial activities of crude ethanol extracts of leaves, stem and blooms from Hyptis suaveolens against bacteria- Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis and Proteus vulgaris and, fungi- Aspergillus nigar and Candida albican. Antimicrobial properties of Hyptis suaveolens were evaluated using cup-plate diffusion and disc diffusion method. Analysis of the data revealed that, the ethanol extract of the blooms exhibited the highest antibacterial activity. It showed antibacterial activity against S. aureus: 34 mm, B. subtilis; 36 mm, E. coli; 35 mm, P. valgaris; 21 mm and P. aerguinosa; 17 mm. The ethanolic extract of the stem showed the highest antifungal activity on C. albican (39 mm). A. nigar was very sensitive to the ethanol extract of the leaves (35 mm). Results were compared to standard drugs; gentamicin and clotrimazole. Based on the current findings, it can be concluded that this Hyptis suaveolens flowering tops has antimicrobial activity, which is as significant as standard antimicrobial drugs against certain microorganisms. Keywords: Hyptis suaveolens, Ethanol, Blooms, Antifungal, Antibacterial.