ABSTRACT Purpose of the present study is to evaluate the correlation between high level of anticardiolipin antibodies (aCL) and recurrent spontaneous abortions in Saudi women. An association between anticardiolipin antibodies and gestational age of abortion and duration past abortion in Saudi women living in Western region of Saudi Arabia (Makkah) was determined by collecting blood samples from 100 females who had history of spontaneous recurrent abortion as case group and 100 pregnant healthy women as control group ages ranged between 20 and 40 years, with a mean age of 31.4 ± 12.69 years. Average rate of anticardiolipin antibodies in the serum of case group compared with the control group in this study indicated significantly low level in case group (p