Objectives: To determine the association of anthropometric indices with type 11 diabetes mellitus, hypertension and hyperlipidemia in Shifa Foundation Falahi Clinic, Islamabad Pakistan. Methods: This cross sectional study was conducted in Shifa Foundation Falahi Clinic, Islamabad to determine the association of obesity related indices like waist circumference (WC), waist to hip ratio (WHR), & body mass index (BMI) with type II diabetes mellitus, hypertension and hyperlipidaemia. A total of 328 patients were included. The blood pressure, fasting blood sugar (FBS) and lipid profile was also performed. The correlation and significance was determined among dependent and independent variables. Results: The mean age of the patient was 47.14 + 11.07. There was 220 (67.1%) female and 108 male (32.9%). The frequency distribution of BMI revealed that only 37 female patients (16.8%) were normal, while 27 male patients (25%) had normal BMI. The diabetes mellitus was present in 164 (50%) of the patients. Hypertension was present in 170 (51.82%) patients. The WC, WHR & BMI has a positive correlation with hypertension and statistically significant. The WC also has a positive correlation with type 11 diabetes mellitus and TG. Conclusion: The study results concluded that the anthropometric indices (WC, WHR & BMI) has a positive correlation with hypertension and statistically significant. The WC also has a positive correlation with type 11 diabetes mellitus and triglyceride (TG). Further community based studies are required to ascertain the findings of this study.