Appendicitis is the most common-intra-abdominal condition requiring emergency surgery, with a 7% lifetime risk. We have retrospectively studied the histomorphology of different disease process affecting the appendix over a period of two years from april 2016 to april 2014. The appendectomies done primarily for appendicular pathology, received at histopathology section of our department were included and those resected along with other organs like hysterectomy and colectomy specimens were excluded from the study.The tissues were processed in routine manner and paraffin embedded blocks were prepared. Serial sections of 4µm to 5µm were cut from the block and processed and stained with haematoxylin and eosin stains. Zeihl Neelson stain was done to confirm the presence of acid fast bacilli in one case. Pathological reports were analyzed for the following parameters: age, gender, and pathological diagnosis. A total of 116 specimens were analyzed. 44 % cases were males and 56% were females. The histopathological examination showed acute inflammation in 57.75% cases , chronic inflammation in 37.93% cases , granulomatous appendicities in 1 case .Parasites were found in 2 cases and carcinoid tumor in 1 case . The vermiform appendix continues to be frequently encountered surgical pathology specimen. Our knowledge about diseases of appendix, is far from complete. This organ therefore requires careful and systematic study both by the clinician and the pathologist.