Diabetes and malnutrition is very common in population. Further its chances increases during pregnancy. when pregnant women suffer by these condition, their fetus also affected. Diabetes and malnutrition affects women’s body so placenta which is formed during pregnancy affect and consequently morphological structure and function of placenta (transfer of nutrition and gaseous exchange ) affect. Maternal blood circulation also affected, hyperglycemia in diabetes and hypoprotenimia in malnutrition. So fetus suffer and consequently newborn baby born with some minor (macrosomia in diabetes and low birth weight in malnutrition) or major (diabetes and protein-energy malnutrition syndrome respectively) pathology.