British Journal of Medical and Health Research BJMHR 2394-2967 BJMHR0207003 Assessment of Liver Enzymes, Zinc and Magnesium Levels in Homozygous Sickle Cell Disease Patients at Aljazeera State, Sudan Ahmed Ibrahim O Idries Omer F Faculty Of Medical Laboratories Science, Department Of Clinical Chemistry, University Of Alneelain, Khartoum, Sudan Faculty Of Sciences And Technology, Department Of Biochemistry And Molecular Biology University Of Alneelain, Khartoum, Sudan 07 01 2015 2 7

Assessment of serum liver enzyme and trace element levels was carried out in a total of hundred (100) subjects comprising seventy (70) sickle cell disease patients attending Madani learning hospital comparatively with thirty (30) apparently healthy persons as control subjects. Blood samples were collected from participants, they were analyzed for trace elements using atomic absorption spectrophotometer. The enzymes activities for serum glutamic oxaloacetic transamineses (SGOT), serum glutamic pyruvic transaminases (SGPT), and Alkaline phosphatase (ALP) were measured using the kinetic tests depending on the reaction with the substrates (2.4-dinitrophenylhydrazine and P. Nitro phenyl). The mean serum level of Magnesium, Zinc, in sickle cell disease patients were 13.1000 ± 1.89 mg/L, 0.40883 ± 0.095 mg/L respectively . Serum magnesium, zinc levels were significantly lower (p

 In Homozygous Sickle Cell Disease liver enzymes zinc magnesium.