1 Anti implantation and Pregnancy Interruption Activity of Japakusuma (Hibiscus rosa Sinensis) & its combinations in Albino Rats

Abstract : Introduction: Population explosion has created grave setback in the economic growth and all-round human development in developing countries. Current pandemic population explosion demands an immediate betterment of new potential contraceptives Easy availability and acceptability of contraceptive help the poorer countries to cut down the population growth and all other nations to avoid maternal morbidity and mortality arising from unplanned pregnancies. Hormonal steroids or various forms of barrier designs are predominantly used contraceptives methods. Studies of many years have highlighted the unmet demand for safe, inexpensive and acceptable contraceptives to avoid unwanted pregnancies Oral contraceptives have been mentioned in Ayurvedic classics like 1) Pippali (Piper longum), + Vidanga (Emblica ribes) + Tankana (Sodii Biboras). 2) Talisapatra (Taxus baccata) + Gairika (Hematite) with cold water 3) Japakusuma (Hibiscus rosa Sinensis) Kanji bhavita (Triturated with sour gruel) Experimental studies on above mentioned 1, 2 & 3 formulations have been proved as temporary contraceptive medicine at BLDEA’s AVS PGCRC Ayurveda Mahavidyalaya Bijapur. To evaluate the permanent or long term temporary contraceptive effect of Japakusuma (Hibiscus rosa Sinensis) Kanji bhavita (Triturated with sour gruel) in combination with Pippali (Piper longum) Vidanga (Emblica ribes) and Tankana (Sodii Biboras) an attempt was made in this study & compared with Individual drug effect. Method: Study was carried out by Choudary and Khanna method on 18 female, 36 male (for mating) albino rats. Pippali (Piper longum) Vidanga (Emblica ribes) Tankana (Sodii Biboras) Japakusuma (Hibiscus rosa Sinensis) Kanji bhavita (Triturated with sour gruel) formulation, Japakusuma (Hibiscus rosa Sinensis) Kanji bhavita (Triturated with sour gruel) and Propylene glycol, formed the materials. Single dose was administered on proestrous stage of rat oestrous cycle & observed for anti implantatio

Keyword : Anti implantation, Pregnancy interruption activity, Japakusuma (Hibiscus rosa Sinensis) Kanji bhavita (Triturated with sour gruel), Pippali (Piper longum), Vidanga (Emblica ribes), Tankana (Sodii Biboras)